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KMID : 0984720080400020067
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Infection and Chemotherapy
2008 Volume.40 No. 2 p.67 ~ p.75
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Recent Evidences of Sepsis Treatment
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Choi Jung-Hyun
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Abstract
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Severe sepsis and septic shock are conditions with a mortality rate about 50% despite of advances of antimicrobial treatment and supportive cares. Recently, investigators are trying to establish a scientific basis for identification of high-risk patients, or a standard practice for hemodynamic optimization and adjunctive pharmacologic therapies for these patients. Several randomized, controlled trials and meta-analyses about certain therapies showed significant reduction of mortality and morbidity. This article is a clinical review of contemporary management strategies recommended with evidences for severe sepsis and septic shock.
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KEYWORD
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Sepsis, Septic shock, Evidence-base medicine
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